Lung Volume Change Between Noninvasive Positive Pressure Ventilation by Nasal Pillow and High Flow Nasal Cannula

The Difference of Lung Volume Change Detected by Electrical Impedance Tomography (EIT) Between Noninvasive Positive-pressure Ventilation (NIPPV) Support by Nasal Pillow and High Flow Nasal Cannula in Post-extubation Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02292992

Enrollment

Registered

2014-11-18

Start date

2014-12-31

Completion date

2015-10-31

Last updated

2014-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Failure

Keywords

Electrical impedance tomography, Nasal Pillow Continuous Positive Airway Pressure(CPAP), High Flow Nasal Cannula, extubation

Brief summary

The difference of lung volume change will be monitored by electrical impedance tomography before and after use of noninvasive positive pressure ventilation by nasal pillow and high flow nasal cannula in post-extubation patients.

Detailed description

Electrical impedance tomography can effectively monitor the lung volume change in ICU patients who were under mechanical ventilator or noninvasive positive pressure ventilator support. Continuous positive airway pressure (CPAP) support by nasal pillow and high flow nasal cannula can improve inspiratory function in extubated patients . However, the extent of lung volume change or functional residual volume (FRC) change by using these two devices were never surveyed before in extubated patients. The investigators will check end-expiratory lung volume (EELV) ,anterior, medio-anterior, medio-posterior and posterior EELV by electrical impedance tomography after use of these two devices in extubated patients.

Interventions

DEVICENasal Pillow CPAP

Nasal Pillow CPAP in extubated patients

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* \>20 y/o * Any extubated patients after tolerating spontaneous breathing trial

Exclusion criteria

* Presence of tracheostomy * Recent facial trauma * Active gastro-intestinal bleeding * Do-not-intubate status and * Planned use of BiPAP after extubation. * Patients with unstable spinal lesions or fractures. * BMI\> 50 * Patients with a cardiac pacemaker * Burn injury with skin defect

Design outcomes

Primary

Measure	Time frame
• End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP	at day 1

Secondary

Measure	Time frame
Anterior, medio-anterior, medio-posterior and posterior EELV at each time	at day 1

Countries

Taiwan

Contacts

Primary ContactKuo Li Kuo, MD

lmn4093@gmail.com+886975835135

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026