to Investigate the Pharmacokinetic Interactions and Safety Between Rosuvastatin and Ezetimibe in Healthy Male Volunteers

A Phase I Clinical Trial to Investigate the Pharmacokinetic Interactions and Safety Between Rosuvastatin and Ezetimibe in Healthy Male Volunteers

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02289430

Acronym

NVP-1205

Enrollment

Registered

2014-11-13

Start date

2014-12-31

Completion date

2015-02-28

Last updated

2016-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

The purpose of this study is to compare the drug interaction of pharmacokinetics of rosuvastatin and ezetimibe.

Detailed description

drug interaction : rosuvastatin, ezetimibe

Interventions

DRUGCrestor+Ezetrol

rosuvastatin+ezetimibe

DRUGEzetrol

ezetimibe

DRUGCrestor

rosuvastatin

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

19 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy male subjects age between 19 and 45 singed informed consent

Exclusion criteria

* Hypotension or hypertension has a history of allergy reaction of this drug or other drugs

Design outcomes

Primary

Measure	Time frame
Area Under Curve	0-24h

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026