BPH
Conditions
Brief summary
Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.
Interventions
None listed
Sponsors
Yonsei University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
65 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. Above 65years of age 2. American Society of Anesthesiologists (ASA) Physical Status I, II, III. 3. undergoing transurethral resection of the prostate(TURP)
Exclusion criteria
1. severe coagulopathy or bleeding disorder(platelet count\<75000, PT INR \>1.2) 2. short stature (under 150 cm) 3. underwent coronary artery bypass graft 4. contraindications of regional anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diastolic function by TTE | The participants will be followed for the duration of surgery (TURP), an expected average of 1 hour. |
Outcome results
None listed