Satiety Response
Conditions
Brief summary
This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.
Detailed description
This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.
Interventions
DIETARY_SUPPLEMENTProcessed orange juice
3 different formulation of edible orange drinks
Sponsors
PepsiCo Global R&D
University of Reading
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Gender: male or female(postmenopausal women only) * Age at start of the study: males ≥ 21and ≤ 65 years and females ≥ 50 and ≤ 65 years * Body Mass Index (BMI) ≥ 18.5 and ≤ 27 kg/m2 * Apparently healthy: measured by questionnaire, no reported current or previous metabolic diseases or chronic gastrointestinal disorders * Reported dietary habits: no medically prescribed diet, no slimming diet, used to eating 3 meals a day * Reported intense sporting activities ≤ 10h/w * Reported alcohol consumption ≤21 units/w * Informed consent signed * Recruitment form filled out
Exclusion criteria
* Smoking * Dislike, allergy or intolerance to test products * Possible eating disorder (measured by SCOFF questionnaire score \>1) * Eating habits questionnaire score \>14 * Reported medical treatment that may affect eating habits/satiety * Pre menopausal women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Self reported hunger and fullness score by Visual Analogue Scale | baseline to 2 hours |
Secondary
| Measure | Time frame |
|---|---|
| Overall liking by '9 point hedonic scale' | baseline to 2 hours |
Countries
United Kingdom
Outcome results
None listed