Psychophysiological Effects of Thorax Wraps With Ginger and Mustard Flour

Psychophysiological Efficacy of Thorax Wraps With Ginger or Mustard Flour in Comparison to Wraps With Warm Water in Healthy Subjects - a Randomized, Placebo-controlled, Three-armed Study With Cross-over Design

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02285452

Acronym

SWI_02

Enrollment

Registered

2014-11-07

Start date

2014-11-01

Completion date

2015-04-01

Last updated

2026-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

physiologcal phenomena, respiratory activity, thorax wraps, HRV Parameters

Brief summary

In integrative medicine wraps are applied for different indications. In this study the effects of thorax with ginger and mustard flour are investigated under standardized conditions. Heart rate variability, well being, warmth distribution and respiratory activity of healthy subjects will be measured.

Detailed description

The purpose of this study is to investigate the effects of different thorax wraps in healthy subjects. Subjects undergo three different interventions (wraps with ginger flour, mustard flour or warm water (placebo)) on three different days. Heart rate variability and respiratory activity is measured for ten minutes before, during (up to 20 minutes) and for ten minutes after each thorax wrap. To investigate the effects on heat development and regulation, photos are taken with a thermographic infrared camera at various moments in time. Participants are asked to fill in questionnaires referring to their subjective perceptions of warmth, bodily warmth distribution and wellbeing. The order of the thorax wrap interventions is randomized.

Interventions

DRUGZingiberis Rhizoma plv.

DRUGSinapis nigrea semen

DRUGPlacebo

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Signed informed consent.

Exclusion criteria

Inflectional disease with body temperature \> 38 °C. Skin damage on the thorax area Known intolerance or hypersensitivity to mustard or ginger products. Heart failure. Asthma bronchiale. Taking medication with influence on heart rate variability ( mainly tricyclic antidepressants and beta blocker). Consumption of coffee or nicotine less than three hours before the intervention. Pregnancy. Deficient knowledge of the German language.

Design outcomes

Primary

Measure	Time frame	Description
changes in temperature	max. 40 minutes	Temperature (in °Celsius) of feet, lower legs, hands and face measured with a thermographic infrared camera (pre-post-comparison)
Respiratory activity (expiratory CO2 and NO-measurement)	max. 40 minutes	Physiological parameters are measured for pre-post comparison.

Secondary

Measure	Time frame	Description
Basler Mood Questionnaire (BBS)	40 minutes	filled in by the participants nine times (before and after the thorax wrap and 10 minutes after the intervention)
Herdecker Wärmeempfindungs-Fragebogen (HeWef)	40 minutes	filled in by the participants nine times (before and after the thorax wrap and 10 minutes after the intervention)
Warmth perception and skin irritation (NRS)	40 minutes	Warmth perception and skin irritation during the intervention every minute (measured with a numeric rating scale).
heart rate variability -Parameter (HRV)	Physiological parameters are measured over a period of 40 minutes	Standard Deviation of Normal to Normal (heart rate) (SDNN)

Countries

Germany

Contacts

PRINCIPAL_INVESTIGATORJan Vagedes, Dr.

ARCIM-Institute

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 17, 2026