Peribulbar Anesthesia
Conditions
Keywords
local anesthesia, peribulbar anesthesia, DEXMEDETOMIDINE, vitreoretinal surgery
Brief summary
During LA in retinal surgery there is some problem as regard the lack of anaesthesia duration and unexpected globe movement .so many adjuvant was added to LA to overcome this disadvantages of LA such as clonidine and fentanyl . The investigators hypothesis is adding dexmedetomidine to pribulbal blocking LA will prolong anaesthesia duration and improve globe akinesia and decrease intraoperative supplementation of LA.There are Many studies had described the effects of dexmedetomidine on peripheral nerve blocks, spinal but up to date no knowledge is available on the impact of dexmedetomidine adjuvant to local anaesthetic in ophthalmic surgery
Interventions
DRUGDEXMEDETOMIDINE
Does adding 5 or 10 micron of DEXMEDETOMIDINE to peribulbar anesthesia is any different from regular peribulbar anesthesia practice?
Sponsors
King Saud University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
40 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients * Going for elective vitreoretinal surgery.
Exclusion criteria
* History of coagulation abnormalities. * Allergy to local anesthetics. * Cardiac, hepatic or renal failure, * Chronic clonidine or analgesic therapy. * One-eyed patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| onset, duration of the motor and sensory block | 10 minutes from injection | A block was considered satisfactory when complete akinesia occurred. In the absence of complete akinesia in any direction after 10 min, supplementary anesthesia given by a further injection of 2-4 ml of the test solution in the same manner as given before. Calculate the number of patients needed supplemental block were. The surgeon assessed the duration of surgery anesthesia and akinesia. Intraocular pressure measured before block, immediately after block and before surgical procedures |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| observe the adverse effects of Dexmedetomidine | during and after surgery | ECG, invasive BP and pulse oximetry will apply to all patients. • The haemodynamic parameters (MAP and HR) will be continuously measured, and will be recorded at before induction (baseline), one minute after block . after 5 minutes then at the surgical incision, 15-min intervals intraoperatively, the end of surgery and10 and 20 minutes postoperatively. Incidence of Oculocardiac reflex (OCR) or any arrhythmia during surgery. |
Countries
Saudi Arabia
Outcome results
None listed