Swiss Longitudinal Cohort

Conditions

Cardiovascular Risk Factors

Brief summary

The planned research project is a prospective population-based cohort study, similar to the well-known Framingham study in the United States. So far, there is no similar research project in Switzerland. It is planned to examine of three Swiss municipalities. Recruitment in a first Swiss municipality (Lostallo/Cama GR) started 2014 and ended in 2019. Overall, 496 participants were recruited in this municipality. The five-year follow-up in this municipality started in 2019. It is planned to start recruitment in a second Swiss municipality (Uznach SG) in 2020. The examinations embrace a broad spectrum of measurements (for details the investigators refer to the published study protocol).

Lucrezia Pusterla, Dragana Radovanović, Franco Muggli, Paul Erné, Andreas W. Schoenenberger et al. (11 authors)

Cardiology and Therapy2022-09-246 citations

10.1007/s40119-022-00280-8

Prevalence of ideal cardiovascular health in a community-based population – results from the Swiss Longitudinal Cohort Study (SWICOS)

Andreas W. Schoenenberger, Dragana Radovanović, Franco Muggli, Paolo M. Suter, Renate Schoenenberger-Berzins et al. (9 authors)

Swiss Medical Weekly2021-09-285 citations

10.4414/smw.2021.w30040

Protocol of the Swiss Longitudinal Cohort Study (SWICOS) in rural Switzerland

Andreas W. Schoenenberger, Franco Muggli, Gianfranco Parati, Augusto Gallino, Georg Ehret et al. (9 authors)

BMJ Open2016-11-019 citations

10.1136/bmjopen-2016-013280

Interventions

OTHERNo intervention

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Resident of Cama GR, Lostallo GR, or Uznach SG * Age ≥6 years (no upper age limit), for voluntary blood sample ≥18 years * Willing to participate in long-term study * Written informed consent (in participants ≥6 years and \<18 years signed by parents)

Exclusion criteria

* No

Design outcomes

Primary

Measure	Time frame
Mortality	10 years

Secondary

Measure	Time frame	Description
Cardiovascular events	10 years	Cardiovascular events (i.e. stroke, myocardial infarction) will be assessed using questionnaires and case records.
Heart function	10 years	Heart function will be assessed using questionnaires for symptoms, clinical examination and measurement of electromechanical activation time.
Cognitive function	10 years	Cognitive function will be assessed using validated instruments.
Autonomy	10 years	Autonomy wil be assessed using validated instruments.
Nursing home admission	10 years	Nursing home admissions will be assessed using standardized questions.
Kidney function	10 years	Kidney function will be assessed using laboratory measurements.

Other

Measure	Time frame	Description
Changes in cardiovascular risk factors	10 years	Cardiovascular risk factors will be assessed using validated measurements.

Countries

Switzerland

Contacts

Primary ContactPaul Erne, MD

paul.erne@erne-net.ch

Backup ContactAndreas W Schoenenberger, MD

Andreas.Schoenenberger@insel.ch

Outcome results

None listed