Micropore Filters
Conditions
Brief summary
The purpose of this study is to determine whether the use of 0.2/1.2 microliter in-line filter reduces the incidence of severe vasoplegia comparing to the 5 microliter filter.
Interventions
None listed
Sponsors
Johann Wolfgang Goethe University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* all patients
Exclusion criteria
* Younger than 18 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of severe vasoplegia | participants will be followed for the duration of intensive care unit stay, an expected average of 1 week |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Organ dysfunction | participants will be followed for the duration of intensive care unit stay, an expected average of 1 week | Severity of organdysfunction (SOFA-Score), incidence and severity of respiratory failure (Horovitz- Index), incidence and severity of acute kidney failure (RIFLE criteria), incidence and severity of delirium |
| Inflammation | participants will be followed for the duration of intensive care unit stay, an expected average of 1 week | Interleukin-6 |
| Duration of ICU and hospital stay | participants will be followed for the duration of intensive care unit/ hospital stay, an expected average of 1 or 4 week (s), respectively | — |
| In-hospital mortality | participants will be followed for the duration of hospital stay, an expected average of 4 weeks | — |
| Morbidity | participants will be followed for the duration of hospital stay, an expected average of 4 weeks | Incidence of preoperative myocardial infarction, stroke, pneumonia, sepsis and acute kidney failure according to routine documentation |
Outcome results
None listed