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Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early Diagnosis

OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early Diagnosis

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02280343
Enrollment
2
Registered
2014-10-31
Start date
2013-03-31
Completion date
2016-03-31
Last updated
2015-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asbestosis

Keywords

forced oscillation tecnique, lung function, asbestosis

Brief summary

Inhalation of dust containing asbestos results in a process of interstitial pulmonary fibrosis called asbestosis. The Forced Oscillation Technique (FOT) evaluates the respiratory mechanics describing resistive, elastic and inertial properties. We believe that this technique may contribute to the early diagnosis of asbestosis.

Detailed description

The aims of this study were (1) to use the FOT to analyze how respiratory mechanics is affected in patients with asbestos exposed, (2) to identify the best FOT parameters for the diagnosis of respiratory changes in these patients (3) Assess whether the presence of obstructive changes is associated with the smoking habit.The control group (CG) included 24 subjects with normal spirometric data and without a history of smoking or pulmonary disease formed by workers and students UERJ and FioCruz. Volunteers with asbestos exposure were from the Department of CESTEH/ FioCruz, totaling 24 exposed and 7 with diagnoses of asbestosis. The diagnosis of asbestosis was established based on a history of substantial exposure to asbestos dusts and compatible radiological features, together with exclusion of other competing diagnoses. The tests included a standardized questionnaire on respiratory symptoms, clinical evaluation; Plain radiography of the chest; FOT, plethysmography and spirometry, in that order.

Interventions

OTHERevaluated lung function

lung function tests

Sponsors

Rio de Janeiro State University
Lead SponsorOTHER

Study design

Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* diagnosis of asbestosis

Exclusion criteria

* other diseases

Design outcomes

Primary

MeasureTime frame
changes in pulmonary mechanicals1 year

Countries

Brazil

Contacts

Primary ContactPaula Sá, research
paulamorisco@hotmail.com552123340705

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026