Autistic Disorder
Conditions
Brief summary
The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity. The hypothesis of abnormal functioning of the fronto-hippocampal network has been evocated but has never been tested. Hence, the present project will include two complementary assessments conducted on a group of adults aged from 18 to 30 with ASD compared to a control group matched in chronological age and intellectual quotient. The first assessment is devoted to the study of associative memory and its EEG correlates and the second focused on the investigation of perceptual strategies related to associative memory using the technique of Eye-tracking. Both behavioral and imaging data would provide new insights on the relationship between perception and memory in ASD.
Interventions
DEVICEElectroencephalography
BEHAVIORALNeuropsychological assesments
Sponsors
University Hospital, Caen
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Adult between 18 and 30 years old * right handed * affiliated to the french national health care system * ASD only for the group of patients
Exclusion criteria
: * mental retardation * schizophrenia * ADHD * brain injury with lost of consciousness * neurological disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The associative memory index | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| theta and gamma oscillations during the associative memory task | 2 years |
Countries
France
Contacts
Primary ContactBérengère GUILLERY-GIRARD, MCU
Outcome results
None listed