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Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02279472
Enrollment
40
Registered
2014-10-31
Start date
2014-10-31
Completion date
2015-01-31
Last updated
2014-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Angle Closure Glaucoma

Brief summary

The purpose of this study is to analysis changes in anterior segment morphology after laser peripheral lrldotomy measured by optical coherence tomography, and to evaluate treatment effectiveness

Detailed description

In the study ,primary angle closure(PAC) and primary angle closure glaucoma (PACG) will be recruited. Anterior segment optical coherence tomography images captured before and after laser peripheral iridotomy will be analysed to provide objective and reproducible quantification of anterior segment biometric parameters.The outcomes can provide useful information for clinical strategies in the treatment and management of pathology related to angle closure.

Interventions

PROCEDURELaserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia

All the patients will be achieved with pilocarpine 1% for pupil constriction, laser peripheral iridotomy(LPI) is performed using the ophthalmic neodymium: yttrium aluminium garnet laser (Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia) and an VOLK iridotomy contact lens. After LPI, patients will be given topical prednisolone acetate 0.1% for 7 days.

Sponsors

Second Xiangya Hospital of Central South University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

1 .The gonioscopy or UBM examination has confirmed the diagnosis of PACS or PAC 2. Intraocular pressure within 10 to 21 mmHg ，C/D≤0.6 3. Visual field is normal or only show paracentral scotoma 4. Vision or corrected visual acuity ≥0.8 5. Refractive degree no more than 200D 6. Exclude other ocular and systemic diseases \-

Exclusion criteria

1. Corneal macula and other corneal diseases, ocular surface disease or corneal edema 2. Iridocyclitis 3. Ocular trauma and intraocular operation history 4. No fixationFundus lesions such as diabetic retinopathy or retinal detachment 5. No fixation 6. Ocular or systemic application of cortical steroids -

Design outcomes

Primary

MeasureTime frame
Changes in anterior chamber after LPI at 1 month1month

Countries

China

Contacts

Primary ContactHaomin Luo, Ph.D student
lhmqqpp@163.com+86 13875830738

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026