Evaluation of SVV From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery

Evaluation of Stroke Volume Variation Derived From NICOM as a Predictor of Fluid Responsiveness in Prone Position During Spine Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02277353

Enrollment

Registered

2014-10-29

Start date

2014-10-31

Completion date

2015-06-30

Last updated

2015-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid Responsiveness, Non Invasive Cardiac Output Monitoring, Prone Position

Keywords

Fluid responsiveness, NICOM, Prone Position, Stroke Volume Variation

Brief summary

NICOM® is a recently developed noninvasive cardiac output monitoring device, and indices derived from NICOM® such as SVV has been reported to predict fluid responsiveness in the previous studies. However, its usefulness in prone positioning has not been investigated. Thus, the aim of this prospective observational study is to evaluate the usefulness of stroke volume variation (SVV) derived from NICOM® to predict fluid responsiveness in prone patients undergoing spine surgery.

Interventions

OTHERFluid loading to evaluate fluid responsiveness

loading of hydroxyethyl starch 6ml/kg over 10-15min to all patients

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* ASA I or II patients undergoing spine surgery in prone position

Exclusion criteria

* Pre-existing arrhythmic disorders/moderate to severe valvular heart disease/obstructive pulmonary disease (COPD grade \>2), left ventricular dysfunction with LV EF less than 50, preoperative need for inotropics or vasopressors * BMI \>30kg/m\^2 or \<15kg/m\^2 * Preoperative serum Cr \> 1.3mg/dL * Patients with coagulopathy

Design outcomes

Primary

Measure	Time frame	Description
Stroke volume variation from NICOM®	5 min after infusion of bolus fluid	predictability of stroke volume variation from NICOM® for fluid responsiveness

Secondary

Measure	Time frame	Description
pulse pressure variation and stroke volume variation from Flotrac/Vigileo system	5 min after infusion of bolus fluid	Correlation with pulse pressure variation, stroke volume variation from Flotrac/Vigileo system

Other

Measure	Time frame
TPR (total peripheral resistance), TPRI (total peripheral resistance index)	5 min after infusion of bolus fluid

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026