Collection of Human Tissue Samples From the Neck Region for Characterization of Its Molecular and Biochemical Signatures

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02274805

Acronym

Human BAT

Enrollment

Registered

2014-10-24

Start date

2014-11-17

Completion date

2020-12-01

Last updated

2026-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

Brown adipose tissue, Neck surgery

Brief summary

The purpose of the study is to gather tissue (from the neck region), specimens (blood and urine) and medical record data from many patients and store them in one place so that scientists have the information they need to conduct research and learn about new ways to predict, identify and treat illness, specifically those related to obesity and diabetes.

Detailed description

This protocol is designed to actively collect biospecimens (specifically, tissue from the neck region) and clinical data for donation to the TRI-MD, specifically, Dr. Sparks' laboratory. These specimens and data will be available to Dr. Sparks for future research activity in accordance with the Florida Hospital and Translational Research Institute for Metabolism and Diabetes (TRI) policies.

Interventions

PROCEDUREAdults presenting for surgery in the neck area

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adults aged 18 and older presenting for surgery in the neck area * Able to provide informed consent

Exclusion criteria

* Unable to provide informed consent

Design outcomes

Primary

Measure	Time frame	Description
Collection of brown adipose neck tissue	Day of scheduled surgery	Any tissue deemed suitable by the surgeon and/or the research team during the neck surgery for the study's research objectives will be removed and collected for donation to this protocol. When there is enough tissue available, half will be snap frozen for extraction of DNA, RNA and protein. The other half will be cryopreserved for the future production of viable cells. When there is not enough tissue, the person collecting the samples will determine the processing. For research purposes, we aim to collect up to 500mg of each tissue.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORLauren Sparks, PhD

Translational Research Institute for Metabolism and Diabetes

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 18, 2026