Ultrasound Guided Thoracic Paravertebral Block for Hepatic Tumors Ablation

Ultrasound Guided Thoracic Paravertebral Blocks: An Effective Pain Control in Percutaneous Radiofrequency Ablation of Hepatic Tumors

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02271646

Enrollment

Registered

2014-10-22

Start date

2014-08-31

Completion date

2015-03-31

Last updated

2019-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cancer

Keywords

paravertebral block, ultrasound guided

Brief summary

Patients undergo percutaneous radiofrequency ablation of hepatic tumors at Siriraj hospital normally receive only intravenous sedative drugs which sometimes can not provide effective pain control. TPVB is suitable for unilateral operations. And it is increasing popular nowadays because of using ultrasound guided which make it is more reliable and has less side effects especially the severe one such as pneumothorax. To cover all nerve supply liver, we decided to use right TPVB at T5-6, T7-8, and T9-10. The aim of this study is to prove that TPVB can provide an effective pain control for patients undergo liver RFA both at rest and movement (cough). We are going to measure the pain score at recovery room and the effective pain control means patients has mild pain (pain score less \</= 3 and do not ask for analgesic drugs).

Interventions

DRUG0.5% marcaine 20ml

3 levels ultrasound guided thoracic paravertebral block at T5-6, T7-8 and T9-10 (total 0.5% marcaine 20ml)

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \> 18 years * Patients undergo percutaneous radiofrequency ablation for liver tumors * ASA classification 1-3

Exclusion criteria

* Psychiatric illness * Chronic abdominal pain \> 1 week * Regular analgesic drugs use * Infection at back (Block area) * Severe spinal deformity * PT \> 16 sec, aPTT \> 32, platelet \< 50,000/cumm

Design outcomes

Primary

Measure	Time frame	Description
pain score at recovery room both at rest and movement (cough)	Up to 24 hours	All patients at recovery room has mild pain (pain score \</= 3) and do not need any rescue analgesic drugs.

Secondary

Measure	Time frame	Description
Distribution of local anesthetic drugs after performing ultrasound guided TPVB at T5-6, T7-8 and T9-10.	After performing TPVB at 5, 10, 20 and 30 minutes.	Test with cold sensation.

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026