Effects of an Oxymizer® During Daytime in Patients With Pulmonary Fibrosis (IPF)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02268981

Enrollment

Registered

2014-10-20

Start date

2014-09-30

Completion date

2015-09-30

Last updated

2015-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Pulmonary Fibrosis

Keywords

Oxymizer, Oxygen conserving device, Conventional nasal cannula (CNC), Idiopathic pulmonary fibrosis

Brief summary

This study will investigate the effects of a reservoir nasal cannula (Oxymizer®) compared to a conventional nasal cannula (CNC) in patients with idiopathic pulmonary fibrosis.

Detailed description

Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program. They will perform the following three interventions on consecutive days and will repeat them after a week. During these days the time table for prescribed physical activities and therapies will be kept in a comparable fashion. The following 3 interventions will be performed in randomized order: Day A: The Patient wears a conventional nasal cannula for 12 h with oxygen flow rate as prescribed during ADL Day B: The Patient wears the Oxymizer® with prescribed oxygen flow rate for 12 h during ADL Day C: The patient wears the Oxymizer® with a flow rate reduced by 1l/min in comparison to the prescribed oxygen flow rate, for 12h The following week the same measurements will be repeated. The mean of the corresponding two measures will be calculated for each approach.

Interventions

DEVICEOxymizer® compared to CNC

Oxygen Saturation measurement for 12 h with CNC

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

30 Years to 80 Years

Healthy volunteers

Inclusion criteria

* IPF patients with indication for long term oxygen therapy ≥ 2l/min * VC \>30% and \< 70% pred.

Exclusion criteria

* failure to comply with study process * acute infection

Design outcomes

Primary

Measure	Time frame	Description
Difference in oxygen saturation between Oxymizer and conventional nasal cannula	day 1 to 13	Oxygen Saturation will be measured via pulseoxymetry for 12 hours. On 2 days, mean oxygen Saturation will be reported while using Oxymizer or a conventional nasal cannula, both with similar Oxygen flow. The difference of the mean Oxygen Saturation of 12 hours between both cannulae will be the Primary outcome.

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026