Breast Cancer
Conditions
Keywords
breast cancer, screening, ultrasound, risk model
Brief summary
In the present study, the investigators will screen breast cancer of the Chinese women based on ultrasound and aim to compare the risk evaluation model of PUMCH model which was established by our previous work with other risk models.
Detailed description
Early detection of breast cancer through screening has been a common practice in the United States and several European countries for decades. It is effective in reducing the mortality of breast cancer and improving the postoperative quality of life of patients. Mammography has been the standard imaging method for the screening, however, our previous study has shown that ultrasound is more sensitive and less expensive than mammography. In the present study, the investigators will screen breast cancer of the Chinese women based on ultrasound and aim to evaluate the risk model (PUMCH model) which was established by our previous work.
Interventions
OTHERultrasound plus clinical breast examination
all the participants will be required to fill risk factor questionaires and then be screened with ultrasound plus physical examination every year
Sponsors
Peking Union Medical College Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
35 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Written informed consent； * residence from community or working units
Exclusion criteria
* pregnancy； * lactation； * known metastatic cancer； * signs or symptoms of breast disease； * presence of breast implants, breast surgery within prior 12 months； * had mammography or ultrasound exam within prior 12 months * males.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of cancer detected in the high-risk group | 3 years |
Countries
China
Contacts
Primary ContactSun Qiang, MD
Backup ContactShen Songjie, MD
Outcome results
None listed