Effects of Male-specific Antibodies on Sex Ratio

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02267252

Enrollment

Registered

2014-10-17

Start date

2014-09-30

Completion date

2025-06-30

Last updated

2023-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sex Ratio, Sperm Antibodies

Brief summary

Investigation of the ability of antibodies from vasectomized men in binding to Y-spermatozoa as a possible explanation of the lower sex ratio observed after microinsemination using epididymal sperm from vasectomized men.

Interventions

OTHERAntibody-sperm binding

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

25 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Vasectomized men

Exclusion criteria

* Men who do not understand the study information

Design outcomes

Primary

Measure	Time frame
Y/X sperm ratio after exposure to sperm-specific antibodies	Up to 28 months

Countries

Denmark

Contacts

Primary ContactJens Fedder, MD, PhD

fedder@dadlnet.dk+45 26820368

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026