Total Occlusive Ionic Silver-containing Dressing vs Mupirocin Ointment Application vs Conventional Dressing in Elective Colorectal Surgery: Effect on Incisional Surgical Site Infection

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02267122

Enrollment

147

Registered

2014-10-17

Start date

2012-01-31

Completion date

2014-01-31

Last updated

2014-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Incisional Surgical Site Infections

Brief summary

The patients were randomized into 3 groups: those patients undergoing a ionic silver-containing dressing (ISD) (Group 1), those undergoing a Mupirocin ointment application (MOA) (Group 2) and those using a conventional dressing (Group 3) in the surgical wound after finishing an elective colorectal surgery.

Interventions

PROCEDUREionic silver-containing dressing

After placing the staples, a ionic silver-containing dressing was placed covering the wound

PROCEDUREMupirocin ointment application

After placing the staples, Mupirocin ointment application over the wound was performed

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Diagnosis of colorectal neoplasms and plans to undergo an elective surgery with curative aims. * Open surgical approach

Exclusion criteria

* Anastomotic leak * Mortality * Lost to follow-up

Design outcomes

Primary

Measure	Time frame
Incisional Surgical site infection	30 postoperative days

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026