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Changes in Renal Artery Movement Due to Respiration Before and After Fenestrated Endovascular Repair

Changes in Renal Artery Movement Due to Respiration Before and After Fenestrated Endovascular Repair

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02266862
Enrollment
0
Registered
2014-10-17
Start date
2015-08-31
Completion date
2015-08-31
Last updated
2017-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fenestrated Endovascular Aortic Repair

Brief summary

Purpose: The purpose of this study is to evaluate the location within the renal artery of maximal angular displacement before and after fenestrated endovascular aortic repair (FEVAR) using CT with end-inspiration and end-expiration CT images before and after repair. Then, the renal artery segment with maximal angular displacement on each will be located and any changes described. Participants: There will be 30 subjects recruited from UNC Hospitals. Procedures (methods): For this study, patients will receive an additional CT sequence (end-expiration CT), which will be compared with the standard of care end-inspiration CT to calculate angular displacement and the distance from the aorta.

Detailed description

The investigators would like to evaluate the location within the renal artery of maximal angular displacement before and after fenestrated endovascular aortic repair (FEVAR) using CT with end-inspiration and end-expiration CT images before and after repair. The investigators would then locate the renal artery segment with maximal angular displacement on each and describe any changes. Because these patients would be getting pre and post-surgical CTs as part of standard of care, there would be no added charge to obtain the information for the study. There would be, however, minimal increased radiation exposure resulting from the extra scan being performed during end-expiration and the patients would have to consent to the slight added risk to participate.

Interventions

RADIATIONStudy group

Patients will receive an additional CT sequence (end-expiration) at the time of their standard CT imaging before and after the repair.

Sponsors

University of North Carolina, Chapel Hill
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Undergoing pre-procedural CT scan for FEVAR

Exclusion criteria

* Has aortic/renal stent already * Cannot receive IV contrast due to renal insufficiency or allergy * Renal arteries are not patent

Design outcomes

Primary

MeasureTime frameDescription
Change in angular displacementBaseline, 6 monthsWe will calculate the distance from the aorta and angular displacement both before and after the procedure. Then, a paired t-test will be used to compare these values to determine statistical significance.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026