Lymphoma
Conditions
Brief summary
Currently there are no official data concerning incidence, progression and prognosis of patients with lymphoma in Brazil.This project aims the establishment of a network of 12 Brazilian Institutions to implement a Lymphoma Registry (RELINFO) with the Brazilian National Cancer Institute (INCA) as the Coordinating Center.We intend to develop and implement a computerized system for data entry and information management of patients with lymphomas. This will enable create a virtual registry of demographic, clinical, epidemiological, histopathological, molecular, and therapeutic data. This clinical record must be linked to histopathological and molecular diagnosis, allowing institutions that work in the context of the public health system have access to new technologies for early cancer diagnosis.We expect is that this record reliably portrays the scene of lymphomas in our state and will become a management model that can be replicated at the national level. Thus, the implementation of RELINFO will strengthen the multidisciplinary diagnosis, promote the standardization of clinical record of patients with lymphomas and provide subsidies to cooperative research projects between participating institutions.
Detailed description
Data collection and management: For data collection will use a common system for all institutions participating.We developed a computerized tool that utilizes models of case report forms (CRF) and allows the inclusion and management of clinical, epidemiological, histopathological and molecular data. The clinical and laboratory data of patients included in RELINFO will be obtained from the hospital records. The integration of local databases allows constitute the RELINFO, conceived as a virtual database of patients with lymphoma. The INCA as Coordinating Center is committed to the security of this database.Standardization of diagnosisThis phase includes structuring a technological platform for the standardization of histopathologic diagnosis (establishing common routines in hematopathology) and the incorporation of molecular methods in the diagnosis of lymphoma.
Interventions
None listed
Sponsors
Adriana Alves de Souza Scheliga
Claudete Esteves Nogueira Pinto Klumb
Ricardo de Sá Bigni
Luciana Wernersbach Pinto
Rocio Hassan
Isabele Avila Small
Monik Mariano Pinto
Cecilia Ferreira da Silva
Claudio Gustavo Stefanoff
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients (adult or child) with diagnosis of Hodgkin's or non-Hodgkin lymphoma with available with available clinical, histopathology and treatment data * Patient enrolled on study sites included on this project
Exclusion criteria
* Patients (adult or child) with other diagnoses of cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| rate of incidence of lymphomas in Brazil | 6 years | Identify the current situation of lymphomas, through the deployment of a Lymphoma Registry in cancer treatment centers of Rio de Janeiro, Brazil |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| epidemiological characterization of lymphomas in Brazil | 6 years | description of demographic, clinical, epidemiological, histopathological, molecular, and therapeutic data of lymphoma patients |
| establishing common routines in hematopathology | 6 years | Structure a technology platform that allows the standardization of histopathological diagnosis and the incorporation of molecular methods in the diagnosis of lymphoma. |
Countries
Brazil
Contacts
Primary ContactClaudio Gustavo Stefanoff, doctor
Backup ContactCecilia F Silva, Master
Outcome results
None listed