Sedentary Lifestyle in Patients Over 70
Conditions
Keywords
PEP'C-R, Endurance parameters, Maximal cardio-respiratory function, Older seniors, Over 70
Brief summary
The primary purpose of the protocol is to determine the effects of a new program of PEP'C PEP'C with constant load and intermittent recovery (PEP'C-R) on endurance parameters of older seniors. The study hypothesis: the investigators propose that PEP'C-R training offers a significant improvement in endurance parameters for older seniors. The secondary objectives are to determine the effects of PEP'C-R on maximal cardio-respiratory function, FMD (Flow-mediated dilation), PWV (pulse wave velocity), systolic and diastolic heart function, body composition (measured by impedance), biological, functional and cognitive functioning and quality of life.
Interventions
OTHERPEP'C-R
Preliminary session of calibration and tolerance: Test of Borg: determination of VT1 for 10 minutes, 3 min pedaling at 25 W and then 20 minutes pedaling on VT1 determined during the exercise test (ET) -10%. Session 1: 30 min of pedaling at constant load VT1 determined during exercise testing (EE) - 10%. Session 2 Session 17: increase in the burden of BASE (5 BASE \* 5 min: 25 min) by 10% and decrease in relation to the load of the PIC (5 PIC \* 1 min: 5 min) to get a cumulative charge of the same session. Changes in heart rate (HR) determine the evolution of sustained loads: a decrease of 10 bpm in heart rate leads to an increase by 10% in the intensity of the base (PIC load remains constant). Session 18 = Session 1.
OTHERControl group usual activities
Participants in the control group will not follow the intervention PEP'C-R. They will continue their usual activities for 9.5 weeks and will be assessed before and after this period. After the study, they will be offered the benefit of the conventional program of the PEP'C.
Sponsors
University Hospital, Strasbourg, France
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
70 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Low physical activity determined using the questionnaire IPAQ in METs (\<3). * Informed about the results of examinations performed at screening visit. * Subject able to understand the purpose, procedures and risks of the study and give written informed consent.
Exclusion criteria
* Contraindications to perform the cardiac stress test and PEP'C-R (Musculoskeletal limitations, Unstabilized heart Failure with chest pain on exertion under maximal medical therapy, ventricular and supraventricular disorders, Acute coronary syndrome within \<1 month, Unstabilized respiratory failure or oxygen-dependent) * Abnormality shown at the cardiac stress test : clinical abnormality (chest pain), electric abnormality (found on ECG), abnormal blood pressure, abnormality of the ventilatory system (bronchospasm, hypoxemia,...) * Cognitive impairment which exclude PEP'C-R training. * Current Cancer chemotherapy. * Visual Impairment which exclude PEP'C-R training. * Presence of fibromyalgia. * Subject treated with beta-blockers and other negative chronotropic molecules. * Acute infection at the time of inclusion. * Dependent patient.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in intensity in W of the first ventilatory threshold (VT1) | From baseline to 9.5 weeks | Determine the intensity in W of the first ventilatory threshold (VT1) for the experimental group and for the control group. |
Countries
France
Outcome results
None listed