Postoperative Laminectomy Pain, Postoperative Pain
Conditions
Keywords
naproxen sodium codeine, paracetamol codeine, disk surgery
Brief summary
Compare the analgesic effects of naproxen sodium codeine, paracetamol codeine and placebo on postoperative pain and tramadol (Contramal) consumption during the first 24 hour after a lumbar disk surgery.
Detailed description
Compare the analgesic effects of naproxen sodium codeine paracetamol codeine and placebo on postoperative pain intensity measured by the visual analogue scale, and evaluated tramadol consumption and related side effects.
Interventions
DRUG550 mg naproxen sodium and 30mg codeine
Postoperative contramal consumption, pain intensity, side effects
DRUG300 mg paracetamol and 30 mg codeine
Postoperative contramal consumption, pain intensity, side effects
DRUGplacebo tablet
Postoperative contramal consumption, pain intensity, side effects
Sponsors
Diskapi Yildirim Beyazit Education and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
16 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists (ASA) 1 or 2 status patients scheduled for an elective lumbar disc surgery
Exclusion criteria
* were known allergies to any of the drugs used in this study * peptic ulcer disease * hepatic and renal dysfunction, * emergency surgery * inability to provide informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Contramal consumption | Postoperative 24 hour | To assess contramal consumption |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Side effects | postoperative 24 hour | nausea and vomiting |
| Pain intensity | postoperative 24 hour | To assess postoperative pain intensity by visual analog scale |
Contacts
Primary ContactReyhan Polat, MD
Outcome results
None listed