Middle Cerebral To Umbilical Artery Doppler Ratio And Amniotic Fluid Volume Measurement In Post-date Pregnancies in King Khalid Military Central City

Middle Cerebral To Umbilical Artery Doppler Ratio And Amniotic Fluid Volume Measurement In Post-date Pregnancies in King Faisal Military Central City

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02255903

Enrollment

200

Registered

2014-10-03

Start date

2022-02-28

Completion date

2023-08-31

Last updated

2022-02-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy, Prolonged

Brief summary

The aim of this study is to assess the values of MCA PI / UA PI and MCA RI / UA RI ratios and amniotic fluid volume in predicting the adverse perinatal fetal outcome in uncomplicated postdate pregnancy

Detailed description

The Study Will be a case-control study that will be conducted at Banha University Hospital and AFHSR in Saudi Arabia after the approval of Institutional ethical committee. One hundred pregnant women will be recruited from antenatal clinic. Starting from November 2022. An informed consent will be obtained from the patients . The patients will be subdivided into two groups: Group 1(Control Group):consist of 100 pregnant females with gestational age 37-40 weeks. Group 2 (post date Group):consist of 100 pregnant females with gestational age 41 weeks or more. Inclusion criteria: 1. Singleton, viable fetus in the vertex presentation. 2. History of regular menstrual cycles. 3. Gestational age calculated from the first day of last menstryal period or by first-trimester or second-trimester (before 20 weeks) ultrasound examination. 4. No obstetric or medical complications of pregnancy apart from post-date pregnancy All patients will be subjected to: 1. Detailed history: including, personal history, menstural history, obstetric history, present history and past history. 2. Physical examination: general, abdominal and pelvic examination. 3. Investigations: including, A- Ultrasound examintion for amniotic fluid index (AFI) measurement. B- Doppler studies: i - Middle cerebral artery pulsatility index (MCA -PI) and resistace index(MCA-RI). ii - Umbilical artery pulsatility index (UA-PI) and resistance index (UA-RI). iii - Cerebro-Placental ratio (CPR).

Interventions

OTHERultrasound and Doppler examination

ultrasound and Doppler examination: Trans-abdominal ultrasound examination will be peformed to all patienst while women in a slightly tilted position with the head of the bed raised 30 degrees and with a small pillow under the right lion

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

19 Years to 48 Years

Healthy volunteers

Inclusion criteria

1. Singleton, viable fetus in the vertex presentation 2. History of regular menstrual cycles 3. Gestational age calculated from the first day of last menstryal period or by first-trimester or second-trimester (before 20 weeks) ultrasound examination 4. No obstetric or medical complications of pregnancy apart from post-date pregnancy

Exclusion criteria

1. Patients unsure of their dates 2. Medical disorders with pregnancy as (hypertension, diabetes mellitus or Rh isoimmunization) 3. Prelabor rupture of membranes 4. Polyhydramnios 5. Women with multiple pregnancy 6. Congenital fetal anomalies 7. Antepartum hemorrhage 8. Previus cesarean section 9. Fetal malpresentation

Design outcomes

Primary

Measure	Time frame
Adverse pregnancy outcome	at time of delivery

Countries

Saudi Arabia

Contacts

Primary Contactkhalid Ibrahim, MD

dr.khalidkhader77@yahoo.com201281469651

Backup ContactKHALID IBRAHIM, MD

966596984055

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026