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Effect of Position During Spinal Anesthesia on Hemodynamic Change in Cesarean Section

Effect of Position During Spinal Anesthesia on Hemodynamic Change in Pregnant Women Undergoing Cesarean Section: Randomized Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02253381
Enrollment
140
Registered
2014-10-01
Start date
2014-10-31
Completion date
2015-03-31
Last updated
2015-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension

Keywords

lateral decubitus position, hypotension, cesarean section

Brief summary

Hypotension is the most common complications after spinal anesthesia especially in pregnant patients who undergoing cesarean section. Position during spinal anesthesia may be altering the hemodynamic. For right lateral decubitus, the enlarged uterus compresses inferior vena cava that may decrease venous return and cardiac output. This leads to hypotension.The hypothesis is the right lateral position during spinal anesthesia in pregnant women will be had hemodynamic changing more than the left lateral position. This objective is to compare hemodynamic change between left and right lateral position during spinal anesthesia in pregnant women undergoing cesarean section.

Detailed description

Study design: A randomized controlled trial Study setting: The study will be conducted in the operating rooms at Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand Study period: The total duration of participation in the randomized study is up to the operative day. Study population: Pregnant patients undergoing cesarean section receiving spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml. Study sample: Inclusion criteria 1. Signed informed consent 2. Pregnancy 3. Spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml 4. Elective and emergency surgery Exclusion criteria 1. Contraindication for spinal anesthesia 2. Complicated pregnancy such as maternal heart disease, eclampsia, severe fetal distress, abruption placenta, twin pregnancy, and placenta previa totalis 3. Maternal height \< 150 cm.

Interventions

PROCEDURERight

Right lateral decubitus position during spinal anesthesia

PROCEDURELeft

Left lateral decubitus position during spinal anesthesia

Sponsors

Prince of Songkla University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* Signed informed consent * Term pregnancy * Spinal anesthesia with 0.5% bupivacaine and 0.2 mg morphine total volume 2.2 ml

Exclusion criteria

* Contraindication for spinal anesthesia * Height \< 150 cm. * Complicated pregnancy e.g. heart disease, preclampsia, eclampsia, diabetes millitus, twin, abrupt placenta, placenta pre via, and fetal distress * Failed spinal anesthesia

Design outcomes

Primary

MeasureTime frameDescription
Hypotensionafter bupivacaine injection until 15 minutes after spinal anesthesiaSystolic blood pressure lower than 90 mmHg or decrease more than 20% of baseline

Secondary

MeasureTime frameDescription
Apgar score at first minute and fifth minuteChild delivery at first minute and fifth minute
Ephedrine consumptionintraoperativeTotal amount of ephedrine receiving

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026