Trapeziometacarpal Arthrosis
Conditions
Brief summary
The investigators are doing this research study to discover factors, such as job, hobbies, or race that are associated with arthrosis at the base of your thumb on X-rays. Thumb arthrosis is one of the most common kinds of arthritis. About 116 people will take part in this research study at Massachusetts General Hospital (MGH).
Interventions
RADIATIONX-Ray
X-ray as part of standard care
Sponsors
Massachusetts General Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 55 years and older * Not seeking care for TMC arthrosis from hand surgeon at the time of visit * english fluency and literacy
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Factors Associated With Eaton Classification of Trapeziometacarpal Arthrosis: Age | Baseline at Day 1 | Radiographs were scored using the Eaton score range.The Eaton score ranges from 1-4 where 1 is the least severe and 4 is the most severe for arthritis. Patients without TMC Arthritis would have a score of 0. Patients' age measured in years. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Factors Associated With Thumb Pain: Hyperextension of Metacarpophalangeal Joint | Day 1, baseline | Thumb pain measured on a scale of 0-10 and dichotomized by having thumb pain (yes/no), hyperextension dichotomized (yes/no) |
| QuickDASH (Disability of the Arm, Shoulder, and Hand) | Day 1, baseline | — |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Patients With Trapeziometacarpal (TMC) Arthrosis Patients presenting to the Orthopaedic Hand Service not seeking care for TMC Arthrosis
X-Ray: X-ray as part of standard care | 59 |
| Total | 59 |
Withdrawals & dropouts
| Period | Reason | FG000 |
|---|---|---|
| Overall Study | Lost to Follow-up | 3 |
Baseline characteristics
| Characteristic | Patients With Trapeziometacarpal (TMC) Arthrosis |
|---|---|
| Age, Continuous | 67 Years |
| Race (NIH/OMB) American Indian or Alaska Native | 0 Participants |
| Race (NIH/OMB) Asian | 2 Participants |
| Race (NIH/OMB) Black or African American | 0 Participants |
| Race (NIH/OMB) More than one race | 0 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 1 Participants |
| Race (NIH/OMB) White | 56 Participants |
| Region of Enrollment United States | 59 Participants |
| Sex: Female, Male Female | 32 Participants |
| Sex: Female, Male Male | 27 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 59 |
| serious Total, serious adverse events | 0 / 59 |
Outcome results
Primary
Factors Associated With Eaton Classification of Trapeziometacarpal Arthrosis: Age
Radiographs were scored using the Eaton score range.The Eaton score ranges from 1-4 where 1 is the least severe and 4 is the most severe for arthritis. Patients without TMC Arthritis would have a score of 0. Patients' age measured in years.
Time frame: Baseline at Day 1
Population: Patients presenting to the Orthopaedic Hand Service not seeking care for TMC Arthrosis~X-Ray: X-ray as part of standard care
| Arm | Measure | Value (MEDIAN) |
|---|---|---|
| Patients With Trapeziometacarpal Arthrosis Eaton Stage I | Factors Associated With Eaton Classification of Trapeziometacarpal Arthrosis: Age | 61 Years |
| Patients With Trapeziometacarpal Arthrosis Eaton Stage II | Factors Associated With Eaton Classification of Trapeziometacarpal Arthrosis: Age | 66 Years |
| Patients With Trapeziometacarpal Arthrosis Eaton Stage III-IV | Factors Associated With Eaton Classification of Trapeziometacarpal Arthrosis: Age | 75 Years |
Secondary
Factors Associated With Thumb Pain: Hyperextension of Metacarpophalangeal Joint
Thumb pain measured on a scale of 0-10 and dichotomized by having thumb pain (yes/no), hyperextension dichotomized (yes/no)
Time frame: Day 1, baseline
Population: All patients with TMC Arthrosis analyzed for hyperextension of MCP joint.
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Patients With Trapeziometacarpal Arthrosis Eaton Stage I | Factors Associated With Thumb Pain: Hyperextension of Metacarpophalangeal Joint | 10 Participants |
| Patients With Trapeziometacarpal Arthrosis Eaton Stage II | Factors Associated With Thumb Pain: Hyperextension of Metacarpophalangeal Joint | 26 Participants |
Secondary
QuickDASH (Disability of the Arm, Shoulder, and Hand)
Time frame: Day 1, baseline
Population: Data were not collected