Atrial Fibrillation and Other Dysrhythmias | Patient
Conditions
Brief summary
Patients with atrial fibrillation are exposed to a high risk of thrombus in the left atrium that can induce cerebral vascular events or systemic embolisms. This justifies the prescription of anticoagulant therapies in patients with high risk of thromboembolic event. Percutaneous left atrial appendage closure is a new interventional strategy for patients with high risk of cardiovascular events and a counter-indication for long term treatment with anticoagulant agents. However, only few data are available on effectiveness and prognosis of patients treated by this new interventional strategy. This national database record per-procedure and follow-up data of patients treated by left atrial appendage closure. This database is strictly observational. Percutaneous left atrial appendage closure is performed only for the purpose of patient care. No specific intervention is performed specifically for the database. Neither left atrial appendage closure procedure nor patient follow up are modified by patient inclusion in the database.
Interventions
OTHERPercutaneous Left Atrial Appendage Closure in routine care
The inclusion in the database induces no specific intervention. Percutaneous Left Atrial Appendage Closure is performed for patient care. No specific intervention is performed specifically for the database. Neither left atrial appendage closure procedure nor patient follow up are modified by patient inclusion in the database.
Sponsors
French association for research in cardiology (ARCARD)
Henri Mondor University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients referred to a french interventional cardiology department for percutaneous left atrial appendage closure in routine care * Signature of an inform consent form for inclusion of data recorded during care in the database
Exclusion criteria
none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the rate of thromboembolic events related to atrial fibrillation in patients treated by left atrial appendage closure in daily practice in France | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Death rate from cardiovascular disease after left atrial appendage closure | 1 year |
| Unexplained Death rate after left atrial appendage closure | 1 year |
| Adverse events related to the procedure | 1 year |
| Assessment of patient management in daily practice after left atrial appendage closure (number of echocardiography procedures) | 1 year |
| Cost of patient follow-up after left atrial appendage closure | 1 year |
| Assessment of patient medical treatment in daily practice after left atrial appendage closure (percentage of patients with antiplatelet drugs) | 1 year |
| Cost of the procedure of left atrial appendage closure | Costs will be assessed for the duration of hospital stay, an expected average of 3 days |
Countries
France
Outcome results
None listed