Stroke, Acute
Conditions
Keywords
Acute ischemic stroke, Acute intracerebral hemorrhage, Transient ischemic attack
Brief summary
A single-center registry of patients with acute ischemic stroke, intracerebral hemorrhage, and transient ischemic attack (TIA) who are emergently managed in the stroke care unit in the National Cerebral and Cardiovascular Center (NCVC) to determine change in underlying characteristics, stroke features and severity, process for diagnosis and acute treatment, and long-term outcomes of stroke/TIA patients over the years.
Detailed description
This is a single-center registry of consecutive patients with acute ischemic stroke, intracerebral hemorrhage, and transient ischemic attack (TIA) who are emergently managed in the stroke care unit in the National Cerebral and Cardiovascular Center, a flagship stroke center in Japan. Neurological emergencies other than stroke/TIA and subclinical cerebrobvascular inpatients are also enrolled. Data are collected and analyzed to determine change in underlying characteristics, stroke features and severity, process for diagnosis and acute treatment, and long-term outcomes of stroke/TIA patients over the years. The National Cerebral and Cardiovascular Center was founded in 1977 in Suita, Osaka, in order to provide the public with the most advanced treatment for cardiovascular and cerebrovascular diseases and to conduct the highest level of basic as well as applied research on the cardiovascular and cerebrovascular systems.
Interventions
OTHERNo intervention
a single-center prospective observational study
Sponsors
National Cerebral and Cardiovascular Center, Japan
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. A patient with acute ischemic stroke, intracerebral hemorrhage, and transient ischemic attack who are emergently managed in the stroke care unit or stroke units in the National Cerebral and Cardiovascular Center (NCVC) 2. Consent to participate in the registration by a patient or relatives obtained using an opt-out approach by the demonstrating contents of the registration on the hospital bulletin board
Exclusion criteria
1\) Patients considered by the investigator to be unsuitable for participating in this registry
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The modified Rankin Scale (mRS), a measure of disability | 3 monhts | mRS scores range from 0 (no symptoms at all) to 6 (death) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants | at entry | Also assessing underlying patients' characteristics prior to index stroke/TIA |
| National Institutes of Health Stroke Scale score | at entry | Also assessing neurological and cognitive states |
| Volume of culprit infarcts/hematoma | at entry | ASPECTS on DWI for ischemia or hematoma volume using the ABC/2 method |
| The modified Rankin Scale (mRS), a measure of disability | around 3 weeks | mRS scores range from 0 (no symptoms at all) to 6 (death). Participants will be followed at hospital discharge, an expected average of 3 weeks. |
| Events of cardiovascular diseases including stroke/TIA | around 3 weeks | Participants will be followed at hospital discharge, an expected average of 3 weeks. |
Countries
Japan
Outcome results
None listed