HIV
Conditions
Keywords
Contest, Crowdsourcing, Innovation, Randomized controlled trial, China, Social entrepreneurship
Brief summary
Crowdsourcing may be a powerful tool to spur the development of innovative videos to promote HIV testing among key populations such as men who have sex with men (MSM) and transgender (TG) individuals. The purpose of this randomized controlled trial is to compare the effect of a crowdsourced video and a conventional video on first-time HIV testing among MSM and TG in China. The crowdsourced video was developed using an open contest, formal transparent judging, and an incentive of marketing promotion. The hypothesis is that a crowdsourced video will be equivalent (within a margin of 3%) to a conventional video in terms of self-reported first-time HIV testing within 3-4 weeks of watching the video.
Interventions
BEHAVIORALConventional Video
Participants will watch a one minute video whose purpose is to increase HIV testing uptake. This video was created by a local CDC via direct CDC funding and internal guidance and development.
BEHAVIORALCrowdsourced Video
Participants will watch a one minute video whose purpose is to increase HIV testing uptake. This video was the winner in a crowdsourced video contest hosted in China. CBOs all submitted their own independently designed and funded videos.
Sponsors
Social Entrepreneurship to Spur Health
University of California, San Francisco
London School of Hygiene and Tropical Medicine
Guangdong Provincial Centers for Skin Diseases and STI Control
University of North Carolina, Chapel Hill
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Born biologically male or identify as transgender * 16 years or older * Lifetime anal sex with another man * Providing informed consent and active mobile phone number
Exclusion criteria
* HIV-infected * HIV-tested ever in the past
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| First-Time HIV Testing | Up to 4 weeks following the video intervention | All individuals enrolled in the study will receive a cell phone text message three weeks later asking if they have received an HIV test. Among those individuals who do not respond to the text message, another text will be sent at four weeks after the video. We anticipate the median duration of follow-up to be approximately 3.5 weeks following the video intervention. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Likelihood of HIV Testing | Up to one day | All individuals will be asked how likely they are to test for HIV soon immediately before and after watching the videos (during enrollment). Likelihood of HIV testing will be measured on a 4-point numerical Likert scale rating scale. 0 will be very unlikely, 1 will be unlikely, 2 will be likely, and 3 will be very likely. The percentage of individuals who report increased likelihood of HIV testing will be reported. |
| Cost-effectiveness of Developing HIV Testing Promotional Videos | Up to one year | Cost-effectiveness of developing the crowdsourced video compared to the conventional video |
Countries
China
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Conventional Video This arm will receive a one-minute conventional video promoting HIV test uptake.
Conventional Video: Participants will watch a one minute video whose purpose is to increase HIV testing uptake. This video was created by a local CDC via direct CDC funding and internal guidance and development. | 369 |
| Crowdsourced Video This arm will receive a one-minute crowdsourced video promoting HIV test uptake.
Crowdsourced Video: Participants will watch a one minute video whose purpose is to increase HIV testing uptake. This video was the winner in a crowdsourced video contest hosted in China. CBOs all submitted their own independently designed and funded videos. | 352 |
| Total | 721 |
Baseline characteristics
| Characteristic | Crowdsourced Video | Total | Conventional Video |
|---|---|---|---|
| Age, Customized 16-20 | 120 Participants | 234 Participants | 114 Participants |
| Age, Customized 21-25 | 136 Participants | 266 Participants | 130 Participants |
| Age, Customized 26-30 | 50 Participants | 112 Participants | 62 Participants |
| Age, Customized 31-35 | 28 Participants | 66 Participants | 38 Participants |
| Age, Customized >35 | 18 Participants | 45 Participants | 27 Participants |
| Annual Income (SD) >15000 | 14 Participants | 30 Participants | 16 Participants |
| Annual Income (SD) <3000 | 113 Participants | 241 Participants | 128 Participants |
| Annual Income (SD) 3000-6000 | 104 Participants | 206 Participants | 102 Participants |
| Annual Income (SD) 6001-9500 | 84 Participants | 169 Participants | 85 Participants |
| Annual Income (SD) 9501-15000 | 37 Participants | 75 Participants | 38 Participants |
| Education College | 231 Participants | 470 Participants | 239 Participants |
| Education Graduate Education | 13 Participants | 38 Participants | 25 Participants |
| Education High School or below | 108 Participants | 213 Participants | 105 Participants |
| Ever used gay mobile application No | 71 Participants | 168 Participants | 97 Participants |
| Ever used gay mobile application Yes | 275 Participants | 542 Participants | 267 Participants |
| Marital status Married/Engaged | 39 Participants | 89 Participants | 50 Participants |
| Marital status Never married | 311 Participants | 615 Participants | 304 Participants |
| Marital status Separated/divorced/Widowed | 10 Participants | 25 Participants | 15 Participants |
| Recent Condomless anal sex Anal sex with a condom | 58 Participants | 115 Participants | 57 Participants |
| Recent Condomless anal sex Condomless anal sex | 28 Participants | 51 Participants | 23 Participants |
| Recent Condomless anal sex No recent sex | 47 Participants | 105 Participants | 58 Participants |
| Sex/Gender, Customized Male | 334 Participants | 685 Participants | 351 Participants |
| Sex/Gender, Customized Transgender | 18 Participants | 36 Participants | 18 Participants |
| Sexual orientation disclosure No | 153 Participants | 312 Participants | 159 Participants |
| Sexual orientation disclosure Yes | 199 Participants | 409 Participants | 210 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | — / — | — / — |
| other Total, other adverse events | 0 / 369 | 0 / 352 |
| serious Total, serious adverse events | 0 / 369 | 0 / 352 |
Outcome results
Primary
First-Time HIV Testing
All individuals enrolled in the study will receive a cell phone text message three weeks later asking if they have received an HIV test. Among those individuals who do not respond to the text message, another text will be sent at four weeks after the video. We anticipate the median duration of follow-up to be approximately 3.5 weeks following the video intervention.
Time frame: Up to 4 weeks following the video intervention
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Conventional Video | First-Time HIV Testing | 111 Participants |
| Crowdsourced Video | First-Time HIV Testing | 114 Participants |
Secondary
Cost-effectiveness of Developing HIV Testing Promotional Videos
Cost-effectiveness of developing the crowdsourced video compared to the conventional video
Time frame: Up to one year
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Conventional Video | Cost-effectiveness of Developing HIV Testing Promotional Videos | The incremental unit cost for promoting HIV testin | 238 USD |
| Conventional Video | Cost-effectiveness of Developing HIV Testing Promotional Videos | The incremental unit costs per newly diagnosed HIV | 799 USD |
| Crowdsourced Video | Cost-effectiveness of Developing HIV Testing Promotional Videos | The incremental unit cost for promoting HIV testin | 131 USD |
| Crowdsourced Video | Cost-effectiveness of Developing HIV Testing Promotional Videos | The incremental unit costs per newly diagnosed HIV | 415 USD |
Secondary
Likelihood of HIV Testing
All individuals will be asked how likely they are to test for HIV soon immediately before and after watching the videos (during enrollment). Likelihood of HIV testing will be measured on a 4-point numerical Likert scale rating scale. 0 will be very unlikely, 1 will be unlikely, 2 will be likely, and 3 will be very likely. The percentage of individuals who report increased likelihood of HIV testing will be reported.
Time frame: Up to one day
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Conventional Video | Likelihood of HIV Testing | Yes | 184 Participants |
| Conventional Video | Likelihood of HIV Testing | No | 185 Participants |
| Crowdsourced Video | Likelihood of HIV Testing | Yes | 212 Participants |
| Crowdsourced Video | Likelihood of HIV Testing | No | 140 Participants |