Gastric Adenoma and Early Gastric Cancer
Conditions
Brief summary
Endoscopic submucosal dissection (ESD) is an advanced technique that enables en bloc resection of superficial tumors in the gastrointestinal tract. ESD, however, is a time-consuming procedure that requires a high level of endoscopic skill to achieve a desirable oncologic outcome. Especially, ESD for the lesion which is located in the antrum of lesser curvature side is difficult. Because the antrum of lesser curvature side is dependent position, irrigated water and blood may prevent visual field of ESD. Generally, whole precutting around the lesion during the ESD is performed prior to dissection. However, it is expected that partial precutting method for the lesion located in the antrum of the lesser curvature may improve the visibility of ESD because it can help us the flap of the lesion evaginated easily. Therefore, we aimed to evaluate the procedure time of ESD for the lesion located in the antrum of the lesser curvature according to the precutting methods (whole precutting vs. partial precutting).
Interventions
PROCEDUREPartial precutting
Partial precutting will be performed prior to dissection during the ESD.
PROCEDUREWhole precutting
Whole precutting will be performed prior to dissection during the ESD.
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Over 19 years old 2. Patients with gastric adenoma or early gastric cancer
Exclusion criteria
1. Patients who has undergone subtotal gastrectomy 2. Patients who has undergone gastrostomy 3. Patients with local recurred gastric adenoma or early gastric cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Procedure time | Within 5 mins after the procedure | Procedure time for the lesion located in the antrum of lesser curvature according to the precutting methods. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| En bloc resection rate | Within 7 days after the procedure | En bloc resection rate according to the precutting methods. |
Other
| Measure | Time frame | Description |
|---|---|---|
| complete resection rate | Within 7 days after the procedure | complete resection rate according to the precutting methods. |
Countries
South Korea
Outcome results
None listed