Neurological; Disorder, Nervous System
Conditions
Keywords
Incurable Neurological Disorders, Autologous mononuclear cell therapy, Stem cells
Brief summary
The purpose of the study was to analyze the benefit of autologous mononuclear cell therapy in incurable neurological disorders.
Interventions
BIOLOGICALStem Cell
Intrathecal autologous bone marrow mononuclear cell transplantation
Sponsors
Neurogen Brain and Spine Institute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Months to 80 Years
Healthy volunteers
No
Inclusion criteria
* diagnosed cases of incurable neurological disorders * age above 6 months
Exclusion criteria
* presence of acute infections such as Human immunodeficiency virus/Hepatitis B Virus/Hepatitis C Virus * malignancies * bleeding tendencies * pneumonia * renal failure * severe liver dysfunction * severe anemia \[Hemoglobin \< 8\] * any bone marrow disorder * space occupying lesion in brain * other acute medical conditions such as respiratory infection and pyrexia * pregnancy * lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in various clinical symptoms of neurological disorders | 1 year | Change in various symptoms such as muscle strength, limb strength, ambulation, neck holding, bladder bowel management, spasticity, sensation, speech, etc depending on the disorder will be recorded at 1 year follow up. Percentage analysis of each symptom will be carried out to study the benefits of stem cell therapy on them. |
Countries
India
Outcome results
None listed