Peri-implantitis
Conditions
Keywords
peri-implantitis, dental implants, randomized controlled trial, non-surgical periodontal treatment, will be defined by the presence of alveolar bone loss of at least 3mm, pocket depth of at least 5mm and bleeding on probing.
Brief summary
This study will compare surgical and non surgical treatments of peri-implantitis. Peri-implantitis is an inflammation around dental implants that can lead to the loss of the implant over time if no treatment is established. The signs of peri-implantitis included bleeding of the gingiva, swelling and redness. Most of times there is no pain. Patients presenting with these characteristics will be included at random to one of the treatment groups. Those allocated to the non-surgical group will received implant cleansing after local anesthesia using adequate instruments. In the surgical group, patients will be submitted to a surgical procedure around the implant for visualization and cleansing also after local anesthesia. All patients will be followed over a 12-month period. The hypothesis is that surgical treatment is better than non-surgical treatment regarding clinical, radiographic, microbiological, and immunological.characteristics.
Interventions
PROCEDURESurgical treatment
Flap surgery around dental implant for scaling and disinfection of the titanium surface under local anesthesia
PROCEDURENon-surgical treatment
Non-surgical subgingival scaling and disinfection of the titanium surface of dental implant under local anesthesia
Sponsors
Federal University of Rio Grande do Sul
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Individuals with at least one dental implant with peri-implantitits * Individuals with good general health conditions; * Individuals presenting at least 10 natural teeth; * Individuals with no signs of active periodontitis
Exclusion criteria
* Individuals who received periodontal treatment in the last three months * Pregnant * Systemic condition that interferes with treatment such as diabetes * Individuals who are taking or have taken antibiotics or anti-inflammatory medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pocket depth reduction | 12 months |
Secondary
| Measure | Time frame |
|---|---|
| Clinical attachment level changes | 12 months |
| Alveolar bone level changes | 12 months |
| Bleeding on probing | 12 months |
| Gingival crevicular fluid immune-inflammatory biomarkers | 12 motnhs |
| Serum biomarkers of inflammation | 12 months |
| Subgingival microbiota changes | 12 months |
Countries
Brazil
Outcome results
None listed