Breast Cancer Female
Conditions
Keywords
Breast cancer, Breast conserving surgery., Radiotherapy., Treatment planning., Prone.
Brief summary
The study purpose is to evaluate whether or not clinical characteristics of women with breast cancer can predict which position for radiation treatment, prone or supine, will be associated with a dosimetry gain. Dosimetry gain in this study means the lowest radiation dose to non-target organs (heart, lungs, contralateral breast), while giving the prescribed dose to tumor bed and ipsilateral breast.
Detailed description
Retrospectively identify women who received curative radiation treatment after breast conserving cancer surgery, in whom simulation in prone and in supine position was performed. Compare the treatment plans for doses to targets and to non-target organs, according to clinical parameters of body mass index, size of breast, location of tumor and side. Furthermore, evaluate whether a single CT slide is enough or not to predict a dosimetry advantage.
Interventions
RADIATIONProne and supine simulation
Treatment planning in the two positions.
Sponsors
Varian Medical Systems
Vincent Vinh-Hung
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Breast conserving surgery * Adjuvant radiation treatment * Simulation done prone and supine
Exclusion criteria
* Simulation in only one position
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Radiation dose to heart and lungs | 4 months | Computations of doses and verification of physics charts. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Radiation dose to tumor bed and ipsilateral breast | 4 months | Computations of doses and verification of physics charts. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Numbers of patients with dosimetry gain in prone position | 2 years | Evaluate the dosimetry gain in subgroups classified according to body mass index, size of breast, side and location of tumor. |
Countries
Switzerland
Outcome results
None listed