Gingivitis
Conditions
Keywords
clinical trial, oral hygiene, Gingivitis, Aloevera, Toothpaste, anti-inflammatory agents
Brief summary
This study aimed to assess the effects of Aloe Vera toothpaste on dental plaque and gingivitis. The single-blind cross-over clinical trial was conducted on 20 dental students (10 males and 10 females with a mean age of 24.5±4 yrs.) with gingivitis. Students were randomly divided into 2 groups. The first group used Aloe Vera toothpaste for 30 days. A 2-week wash-out period was allowed and then subjects used fluoride toothpaste for the next 30 days . This order was reversed in group 2.
Detailed description
Toothpastes are used with tooth brushing to better control microbial plaque. Herbal toothpastes have recently gained attention. This study aimed to assess the effects of Aloe Vera toothpaste on dental plaque and gingivitis. This single-blind cross-over clinical trial was conducted on 20 dental students (10 males and 10 females with a mean age of 24.5±4 yrs.) with gingivitis. Students were randomly divided into 2 groups. The first group used Aloe Vera toothpaste for 30 days and then their plaque index (PI) and gingival index (GI) were recorded. A 2-week wash-out period was allowed and then subjects used fluoride toothpaste for the next 30 days and underwent PI and GI assessment again. This order was reversed in group 2. Wilcoxon-Sign Rank and two way Repeated Measure ANOVA tests were applied for statistical analysis.
Interventions
OTHERForamen Herbal Aloe toothpaste
use of aloe-vera toothpaste for 30 days in the test group.
OTHERfluoride toothpaste
use of signal toothpaste once a day for 30 days in the control group.
Sponsors
Islamic Azad University, Sanandaj
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 24 Years
Healthy volunteers
Yes
Inclusion criteria
* Subjects were selected among dental students with at least 20 natural teeth without systemic disease * No periodontal treatment at least 6 months to the study * No use of systemic antibiotic and anti-inflammatory drugs within the last 3 months, nonsmokers, no pregnancy or lactating women * Subjects with PD≤3mm, (clinical attachment level)CAL\<1mm, PI≥2 and gingival bleeding in more than 30% of the tested areas were enrolled with the diagnosis of plaque-related gingivitis.
Exclusion criteria
* Subjects with orthodontic appliances ,multiple bridges, partial denture, multiple caries were excluded from the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measuring gingival index | 1-2days | to compare the efficacy of the aloe-vera toothpaste with a known conventional toothpaste, the gingival index was recorded at baseline and after 30 days of consumption and compared with the two understudy toothpastes. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| measuring gingival index | 1-2 days | to compare the efficacy of the aloe-vera toothpaste with a known conventional toothpaste, the gingival index was recorded at baseline and after 30 days of consumption and compared with the two understudy toothpastes. |
| measuring plaque index | 1-2 days | to compare the efficacy of the aloe-vera toothpaste with a known conventional toothpaste, the plaque index was recorded at baseline and after 30 days of consumption and compared with the two understudy toothpastes. |
Countries
Iran
Outcome results
None listed