A Comparison of Epidural Block With Adding Sciatic Block to Continuous Femoral Block in Total Knee Arthroplasty

A Comparison of Epidural Analgesia With Adding Sciatic Nerve Block to Continuous Femoral Nerve Block for Post-operative Pain Management Following Total Knee Arthroplasty

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02235506

Enrollment

Registered

2014-09-10

Start date

2014-09-30

Completion date

2016-06-30

Last updated

2015-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Brief summary

The investigators compared continuous epidural infusion with combined continuous femoral and single-shot sciatic nerve blocks. The primary outcome was the incidence of side effects, and secondary outcomes were pain relief, motor blockade,morphine consumption, and rehabilitation indices.

Detailed description

The parcicipants were randomly assingned to epidural infusion group and femoral sciatic block. In epidural infusion group, a lumbar epidural catheter was placed at the L3-4 level using loss-ofresistance procedure. ropivacaine 0.2% and fentayl 2mcg/ml were infused at a rate of 5ml/hr from the end of operation. In femoral sciatic group, the femoral and sciatic nerve are located using ultrasound and 0.2% ropivacain is injected. A catheter is inserted to femoral nerve. From the end of operation, 0.2% ropivacaine was infused through the femoral catheter at a rate of 5ml/hr. The incidence of side effects is measured.

Interventions

PROCEDUREepidural infusion

Lumbar epidural catheter is placed at the L3-4 level using loss-ofresistance procedure. Fentayl 2mcg/ml and 0.2% ropivacaine are infused at a rate of 5ml/hr.

PROCEDUREfemoral sciatic

After femoral and sciatic nerve are identified using ultrasound, 0.2% ropivacaine 20 mL is injected. A catheter is inserted to femoral nerve and 0.2% ropivacaine is infused through the femoral catheter at a rate of 5ml/hr from the end of surgery.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologists Physical Status Classification I-II * total knee arthroplasty * 18-90 years

Exclusion criteria

* allergic to the local anesthetics * cognitive impairment such as dementia * coagulopathy * motor and sensory impairment * patient refusal * BMI \>39

Design outcomes

Primary

Measure	Time frame	Description
the incidence of side effects	during 5 days after the end of operation	Side effects: The patients were asked to their experience of dizziness, sedation, nausea/vomiting (PONV), and pruritus. Urinary retention: bladder volume was measured by ultrasonography and if the volume was more than 400 mL and if the patient was unable to void spontaneously, single catheterization was performed.

Secondary

Measure	Time frame	Description
Pain	during 5 days after the end of operation	Pain according to visual analogue scale at rest and on mobilization.
Motor blockade at rest and on mobilization	during 5 days after the end of operation	Motor blockade is estimated using a modified Bromage scale

Countries

South Korea

Contacts

Primary ContactSangjin Park, M.D.

apsj0718@naver.com82-53-620-3366

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026