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Double-blind, Placebocontrolled A Randomized Trial on the Efficacy of Herbal Galactogogues

Efficacy of Herbal Galactogogues: a Double-blinded, Placebo-controlled Randomized Trial.

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02233439
Enrollment
210
Registered
2014-09-08
Start date
2014-09-30
Completion date
2015-03-31
Last updated
2014-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breastfeeding

Keywords

galactagogues, herbs, breastfeeding, supplements, Silybum marianum, Galega officinalis

Brief summary

The purpose of this study is to assess the effectiveness of a commercially available product containing a combination of Silybum marianum and Galega officinalis to support continuation or augmentation of breast milk production.

Interventions

DIETARY_SUPPLEMENTHerbal galactagogue
DIETARY_SUPPLEMENTPlacebo

Sponsors

Milte Italia SpA
CollaboratorUNKNOWN
Università degli Studi dell'Insubria
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* singleton, term delivery * \>2.5 kg newborn weight * lactation-deficiency

Exclusion criteria

* Neonatal Intensive Care Unit admission * use of galactagogue drugs * allergy

Design outcomes

Primary

MeasureTime frame
Percentage of mothers who exclusively breastfeed their childAt 6 weeks postpartum

Secondary

MeasureTime frame
Rate of breastfeeding (either exclusively or as a supplement to formula feeding )at 6 weeks and 3 months
Volume (mL) and frequency (times a day) of formula6 weeks postpartum
weight gain experienced by the newborns6 weeks postpartum
serum prolactin levelat baseline and 6 weeks after treatment
Rate of maternal allergic reactions and gastrointestinal side effects6 weeks postpartum

Countries

Italy

Contacts

Primary ContactAntonella Cromi, MD
antonella.cromi@uninsubria.it

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026