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Effect of Hypertonic Solutions on Allergic Rhinitis Patients

Do Hypertonic Solutions Have an Impact on Nasal Eosinophilia in Allergic Rhinitis Patients?

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02233426
Acronym
hypertonic
Enrollment
1000
Registered
2014-09-08
Start date
2014-09-30
Completion date
2014-10-31
Last updated
2014-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis

Keywords

allergic rhinitis, nasal steroid, hypertonic saline, eosinophil, symptom score

Brief summary

The purpose of this study is to assess the effectivity of using hypertonic nasal solutions alone on the symptom scores and nasal eosinophil levels of allergic rhinitis patients, retrospectively.

Detailed description

The medical records of the patients who admitted to outpatient clinic of otorhinolaryngology department of a tertiary referral center were retrospectively investigated. The symptom scores and nasal eosinophil levels of the patients were recorded. Patients using hypertonic solutions alone or steroid nasal spray alone were compared.

Interventions

None listed

Sponsors

Namik Kemal University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with positive Prick's test to at least one allergen and diagnosed as having allergic rhinitis were included * Patients who used hypertonic nasal solution alone for at least one month were included as sthe study group * Patients who used nasal steroid spray alone or at least one month were included as sthe study group

Exclusion criteria

* Patients with a history of asthma, urticeria, eczama, diabetes mellitus, hypertension, COPD and other systemic diseases were excluded

Design outcomes

Primary

MeasureTime frame
The number of eosinophils in nasal secretionsThe number of eosinophils in nasal secretions that was counted before the therapy and after the first month of therapy would be recorded

Secondary

MeasureTime frame
Sinonasal Outcome Test (SNOT-22) questionairre scoresSNOT-22 scores obtained before the treatment and after the first month of treatment would be recorded

Countries

Turkey (Türkiye)

Contacts

Primary ContactZafer Ciftci, Assist. Prof
zaferciftci@yahoo.com00905325540605

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026