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Usefulness of Neutrophil Gelatinase-associated Lipocalin(NGAL) to Confirm Acute Kidney Function Decrease of the Patients Who Had Non-cardiac Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02233010
Enrollment
43
Registered
2014-09-08
Start date
2014-02-28
Completion date
Unknown
Last updated
2014-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease

Brief summary

Although post-op renal function decrease is determined by serum creatinine, serum creatinine has disadvantages that it increases a long time after renal function decrease and it has various increasing time based on the level of renal function. Neutrophil Gelatinase-associated Lipocalin (NGAL's) usefulness as an evidence for acute kidney damage occurring from post-op cardiac surgery, being critical patients and contrast medium use is already proven. But NGAL's usefulness for renal function after non-cardiac surgery is not proven and especially, NGAL's usefulness for renal injury after non-cardiac surgery in chronic renal disease patients is not proven.Therefore, the investigators will study about renal function decrease after non-cardiac surgery with NGAL and serum creatinine.

Interventions

OTHERThe level of NGAL after pre op,post op 4hr, post op 12hr

Sponsors

Inje University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 79 Years
Healthy volunteers
No

Inclusion criteria

* 43 patients who had non-cardiac surgery in Seoul Paik Hospital.

Exclusion criteria

* have viral hepatitis and Aspartate aminotransferase, Alanine aminotransferase \> 2 time of normal level * severe lung disease * severe heart failure ( Ejection Fraction \< 40% ) * pregnancy

Design outcomes

Primary

MeasureTime frame
serum NGAL levelup to post operation 12 hours

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026