Influence of Two Different PEEP Niveaus and a Trendelenburg Positioning Manoeuvre on Subclavian Vein Diameter

Influence of Two Different PEEP Niveaus and a Trendelenburg Positioning Manoeuvre on Subclavian Vein Diameter as a Surrogate Parameter in Punctures of Central Veins

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02231463

Enrollment

Registered

2014-09-04

Start date

2014-06-30

Completion date

2015-12-31

Last updated

2016-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insufficiency; Cardiac, Complicating Surgery

Keywords

ultrasound

Brief summary

In 50 Patients who are undergoing a planned surgical procedure which require a central venous catheter the diameter of the subclavian vein is measured by ultrasound under 6 different conditions.

Detailed description

In 50 Patients who are undergoing a planned surgical procedure which require a central venous catheter the diameter of the subclavian vein is measured by ultrasound under 6 different conditions. The conditions are 1. neutral positioning, PEEP 0 cm H2O, 2. neutral positioning, PEEP 5cm H2O, 3. neutral positioning, PEEP 10cm H2O, 4. Trendelenburg positioning -20°, PEEP 0 cmH2O, 5. Trendelenburg positioning -20°, PEEP 5 cmH2O, 6. Trendelenburg positioning -20°, PEEP 10 cmH2O After these measurements a central venous catheter is used to measure the central venous pressure.

Interventions

OTHERneutral positioning, PEEP 0 cm H2O

neutral positioning, PEEP 0 cm H2O

OTHERneutral positioning, PEEP 5cm H2O

neutral positioning, PEEP 5cm H2O

OTHERneutral positioning, PEEP 10cm H2O

neutral positioning, PEEP 10cm H2O

OTHERTrendelenburg positioning -20°, PEEP 0 cmH2O

Trendelenburg positioning -20°, PEEP 0 cmH2O

OTHERTrendelenburg positioning -20°, PEEP 5 cmH2O

Trendelenburg positioning -20°, PEEP 5 cmH2O

OTHERTrendelenburg positioning -20°, PEEP 10 cmH2O

Trendelenburg positioning -20°, PEEP 10 cmH2O

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \>18 years * cardiosurgery or neurosurgery * written informed consent * ECG: inus rhythm

Exclusion criteria

* peacemaker * kontraindications for PEEP * pulmonary disease * hemodynamically instable patients * pregnancy * pulmonal Hypertension * ejection fraction \< 35% * severe valvular disease * tricuspid insufficiency

Design outcomes

Primary

Measure	Time frame	Description
Diameter of vein	only 1 day (the day of the measurement); no follow-up is required	measurement of vein Diameter by ultrasound in a randomized order

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026