Whole Breast RT on Prone Position in Korean Women

Feasibility of Prone Position in Postoperative Whole Breast Radiation Therapy in Korean Breast Cancer Patient

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02231112

Enrollment

Registered

2014-09-04

Start date

2014-11-30

Completion date

2015-09-30

Last updated

2014-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Keywords

Korean, Left side

Brief summary

It is well known fact that postoperative whole breast radiation therapy (RT) in left breast cancer patient can cause cardiac problem according to the exposed dose. In the several studies in other countries, it was repeatedly showed that RT on prone position can reduce cardiac exposed RT dose in left breast cancer. However, the effectiveness of prone position in RT is not studied in the Korean women have relatively small breast. The investigators planned this study to evaluate the real efficacy of prone position in Korean breast cancer treated with RT.

Interventions

RADIATIONWhole breast RT on prone position

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Pathologically confirmed left breast cancer * 20 or older age * less than 70 years old * after curative resection * Eastern Cooperative Oncology Group performance status 0 to 1 * Informed consent to this study * Consent to contraception for 6 months after RT completion

Exclusion criteria

* Male breast cancer * Combined distant metastasis * Status of pregnant or brest feeding * Previous RT history of chest or neck area * Indication of supraclavicular RT * Not indicated postoperative whole breast RT

Design outcomes

Primary

Measure	Time frame
Irradiated cardiac dose	At simulation, expected average of 1 week

Secondary

Measure	Time frame
Irradiated lung dose	At simulation, expected average of 1 week
Clinical target volume (volume, homogeneity index, conformity index)	At simulation, expected average of 1 week
Irradiated dose of left anterior descending artery	At simulation, expected average of 1 week
Skin change after RT	At 3 months after RT completion
Breast shape after RT	At 6 months after RT completion
Irradiated dose of axillary lymphatic area	At simulation, expected average of 1 week

Countries

South Korea

Contacts

Primary ContactDoo Ho Choi, M.D., Ph.D.

doho.choi@samsung.com82-2-3410-2612

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026