Expiratory Flow Limitation and Postoperative Complications

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02229591

Enrollment

330

Registered

2014-09-01

Start date

2013-01-31

Completion date

2016-09-30

Last updated

2016-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Respiratory Complications

Brief summary

Expiratory flow limitation (EFL) occurs when flow ceases to increase with increasing expiratory effort. In any circumstances EFL predisposes to pulmonary dynamic hyperinflation and its unfavorable effects such as increased elastic work of breathing, inspiratory muscles dysfunction, and progressive neuroventilatory dissociation, leading to reduced exercise tolerance, marked breathlessness during effort, and severe chronic dyspnea. Our hypothesis is that EFL should affect post operative outcomes like incidence of pulmonary complication and length of stay in hospital

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* General anesthesia * Duration of the surgery \>2 hours

Exclusion criteria

* \<18 years * Consensus not given

Design outcomes

Primary

Measure	Time frame	Description
Pulmonary complication	28 days	Postoperative pulmonary complication such infection, acute respiratory distress, post operative desaturation

Countries

Italy

Outcome results