Strabismus Measurements Using Automated 3D Video Oculography

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02228070

Enrollment

Registered

2014-08-28

Start date

2015-07-31

Completion date

2016-07-31

Last updated

2017-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabismus

Keywords

strabismus, oculomotor palsy, abducens palsy, trochlear palsy

Brief summary

Measuring ocular motility and alignment is important for diagnosing different causes of strabismus, following patients recovering from cranial nerve palsies, preparing patients for strabismus surgery and follow-up post surgery. The current clinical gold standards for measuring ocular alignment are the Hess screen and the Harms tangent screen. These tests are accurate, but require patient cooperation, and are not objective because the patient has to indicate the position of the light he sees on the screen. Our objective is to develop an accurate and easy to use goggles system to measure ocular alignment and motility using 3D video oculography.

Interventions

DEVICEstrabismus video goggles

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

11 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients 11 years or older * congenital strabismus * acquired strabismus * paretic strabismus (oculomotor, abducens and trochlear nerves) * before and after strabismus surgery * normal controls

Exclusion criteria

* Patients unable to sign informed consent * Patients with significantly impaired vision * Patients unable to cooperate with standard strabismus workup (including Hess and Harms tests) * For sub-study: intolerance to scleral search coils

Design outcomes

Primary

Measure	Time frame	Description
Validation of video goggles against Hess/Harms screen	initial visit	Measurement of squint angle with 3D video goggles vs. Hess/Harms screen.

Secondary

Measure	Time frame	Description
Accuracy of video goggles in comparison to scleral search coils	initial visit	Measurement of squint angle with 3D video goggles vs. scleral search coils.

Other

Measure	Time frame	Description
Follow-up squint angle measures post-OP and after recovery from cranial nerve palsy with 3D video goggles and Hess/Harms screen	initial visit, 3 months after surgery, recovery from cranial nerve palsy after 3 months	Change in squint angle with 3D video goggles and Hess/Harms screen.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026