Healthy Subjects
Conditions
Keywords
fruit, nuts, liver fat, insulin, glucose, Focus of the study is to compare the often given advice to eat fruit, containing large amount of glucose and fructose, with nuts that are more rich in fat.
Brief summary
Recruitment of 28 subjects that will be randomized to consume fruit or nuts as snacks between regular meals for two months. Laboratory tests for cardiovascular risk factors, metabolic rate, liver steatosis and physical activity are investigated ahead of start of the study and at the end of the trial period och two months. Participants will be allowed to buy fruits or nuts on their own but to keep track (diaries) of the amount consumed. They will be reimbursed for the costs of the snacks.
Interventions
DIETARY_SUPPLEMENTFruits
Randomization to extra fruit or nuts as snacks
DIETARY_SUPPLEMENTNuts
Sponsors
University Hospital, Linkoeping
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 76 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy subjects
Exclusion criteria
* significant diseases that can affect outcomes, mental disorders that can affect participation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| amount of fat in the liver by magnetic resonance imaging | two months | exact measurement of fat in the liver by liver spectroscopy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| cardiovascular risk factors | two months | Collection of markers for cardiovascular risk including glucose, insulin, lipoproteins etc. Analyses will be performed from blood samples. |
Countries
Sweden
Outcome results
None listed