Transmuscular Quadratus Lumborum Block for Laparoscopic Cholecystectomy

Ultrasoundguided Transmuscular Quadratus Lumborum Block After Elective Laparoscopic Cholecystectomy. A Prospective, Randomized Clinical Trial.

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02225418

Acronym

TQL

Enrollment

Registered

2014-08-26

Start date

2014-11-30

Completion date

Unknown

Last updated

2015-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis, Pain

Keywords

Laparoscopic, Cholecystectomy, Postoperative, Pain, Quadratus lumborum, Ultrasound

Brief summary

The TQL block may prove a valuable method for treating postoperative pain following scopic removal of the gall bladder. The trial will compare active TQL block versus placebo TQL block after said operation. The hypothesis is that active TQL block significantly will reduce postoperative pain following scopic removal of the gall bladder compared with placebo TQL block.

Interventions

DRUGRopivacaine

DRUGsaline

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* scheduled for elective laparoscopic cholecystectomy * received oral and written information about the trial * American Society of Anaethesiologists (ASA) classification 1-3 * NRS score \> 3 upon arrival at the PACU area

Exclusion criteria

* Cannot cooperate * Does not speak or understand Danish * Allergy towards drugs used in the trial * Large daily consumption of opioids * Known alcohol og medicin abuse * Difficult or impossible by ultrasound to visualise the intended nerve/tissue structures necessary to perform block * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Pain score in sitting position	1 hour	Numerical Rating Scale (NRS) score 1 hour after administration of TQL block

Secondary

Measure	Time frame	Description
Pain score at rest	15 min, 30 min, 1 hour 2 hour 3 hour 4 hour 5 hour	NRS score after administration of TQL block at said time points
Pain score at sitting position	15 min 30 min 2 hour 3 hour 4 hour 5 hour	NRS score after administration of TQL block at said time points
Total opioid consumption in PACU area	On average 3 hours	During stay in PACU area
Opioid side effects (nausea, vomiting)	On average 3 hours	During stay in PACU area
Length of stay in PACU area	On average 3 hours	Total time in PACU area

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026