Multicenter Intervention Program to Optimize the Clinical Management of Community-acquired Pneumonia in Hospitals

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02224716

Enrollment

968

Registered

2014-08-25

Start date

2014-07-31

Completion date

2015-12-31

Last updated

2015-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community Acquired Pneumonia

Brief summary

The purpose of this study is to evaluate the impact of a structured package (bundle) in reducing the use of antimicrobials and hospital stay of patients with community-acquired pneumonia (CAP), and no increase in mortality of these patients in different hospitals.

Interventions

None listed

Study design

Observational model

COHORT

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Diagnosis of CAP at hospital admission . * Age: 18 years or more.

Exclusion criteria

* Patients with nosocomial pneumonia or criteria related to health care. * Patients with severe immunosuppression (HIV infection with \<200 CD4+ lymphocytes / mm3), neutropenia (\<500 neutrophils / mm3). * Patient treated with immunosuppressive drugs.

Design outcomes

Primary

Measure	Time frame	Description
Antimicrobial use in patients hospitalized for CAP.	twelve months	It is measured in defined daily doses (DDD) per 100 hospital stay of patients hospitalized with CAP.
Mortality rate to 30 days	twelve months	Number of death of patients hospitalized with CAP, stratified by CURB-65 score.

Secondary

Measure	Time frame	Description
Appropriate supportive treatment	Twelve months	Implementation of quality indicators in the management of CAP. They are expressed as dichotomous variables (yes / no): Number of doctors who take supportive treatment according to guideline during the hospitalization.
Empirical treatment	Twelve months	Implementation of quality indicators in the management of CAP. They are expressed as dichotomous variables (yes / no): Number of doctors who prescribed empirical treatment according to the guideline at admission.
CAP severity CURB-65 or PSI registered.	twelve months	Implementation of quality indicators in the management of CAP. They are expressed as dichotomous variables (yes / no): Numbers of doctors who register on the clinical history the evaluation of CAP severity by CURB-65 or PSI at hospitalization.
Specific antimicrobial treatment	Twelve months	Implementation of quality indicators in the management of CAP. They are expressed as dichotomous variables (yes / no): Number of doctors who prescribed the specific antimicrobial treatment defined in the guideline
Total duration of antibiotic therapy.	Twelve months	Implementation of quality indicators in the management of CAP. They are expressed as dichotomous variables (yes / no): Number of doctors who prescribe an antimicrobial treatment during 7 days or less, or 5 days or less after clinical improvement.
Appropriate sequential therapy.	Twelve months	Implementation of quality indicators in the management of CAP. They are expressed as dichotomous variables (yes / no): Number of doctors who switch to oral therapy according to guideline.
Microbiological samples at admission.	twelve months	Implementation of quality indicators in the management of CAP. They are expressed as dichotomous variables (yes / no): Numbers of doctors who taking all microbiological samples recommended in the guideline in the first 6 hours of patient admission.

Countries

Spain

Contacts

Primary ContactPilar Retamar Gentil

gestionensayosclinicos.fps@juntadeandalucia.es0034 955 04 04 50

Outcome results