Assisted Reproductive Techniques, In Vitro Fertilization
Conditions
Keywords
IVF, Embryo Quality, Time Lapse Culture, Preimplantation factor
Brief summary
The aims of this study are to evaluate: 1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF. 2. the association between PIF status in embryo culture medium and embryo quality assessed by standard subjective parameters and morphokinetic development.
Interventions
PROCEDUREDay 0 denudation and time lapse culture on IVF-oocytes.
Sponsors
Regionshospitalet Viborg, Skive
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Standard IVF treatment * Body mass Index (BMI) between 18 and 30 * couples in which the male partner has normal sperm concentration and motility according to the World Health Organization (WHO, 2010)
Exclusion criteria
\- Patients with less than four oocytes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Embryo Quality | Day 0-5 after oocyte pick-up |
Secondary
| Measure | Time frame |
|---|---|
| Fertilisation rate | Day 1 after oocyte pick-up |
Other
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate | 7th week of gestation |
Countries
Denmark
Outcome results
None listed