Central Blood Pressure in Adolescents and Young Adults

Diurnal Variation of Central Blood Pressure in Adolescents and Young Adults and Association With Indices of Asymptomatic Target-organ Damage

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02222077

Enrollment

150

Registered

2014-08-21

Start date

2014-07-31

Completion date

2018-02-28

Last updated

2017-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy, Hypertension

Keywords

Central blood pressure, Ambulatory blood pressure monitoring, Target-organ damage, Adolescents and young adults

Brief summary

This study aims to investigate in adolescents and young adults: * the 24h diurnal variation of ambulatory central blood pressure * the association of central compared to peripheral blood pressure with indices of asymptomatic target-organ damage

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

12 Years to 25 Years

Healthy volunteers

Yes

Inclusion criteria

* Adolescents and young adults (age range 12-25 years)

Exclusion criteria

* Subjects with any acute or significant chronic disease, with evidence of secondary hypertension, or on regular drug treatment will be excluded

Design outcomes

Primary

Measure	Time frame	Description
Correlation coefficients (r) between 24h ambulatory central blood pressure and indices of target-organ damage	Assessment of each individual will require up to 3 days	Correlation coefficients (r) will be determined for the relationship between central blood pressure and indices of target-organ damage (left ventricular mass index, carotid intima-media thickness, pulse wave velocity). Also, these coefficients will be compared with z-statistic with the respective ones for the peripheral blood pressure.

Countries

Greece

Contacts

Primary ContactGeorge S Stergiou, Professor of Medicine

gstergi@med.uoa.gr+302107763117

Outcome results