Carotid Artery Occlusive Disease
Conditions
Keywords
Stenting, Endarterectomy, Cognition
Brief summary
This study compares cognitive function after carotid endarterectomy and stenting.
Interventions
PROCEDURECarotid endarterectomy vs. carotid stenting
Sponsors
Baylor College of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Carotid artery occlusive disease, asymptomatic greater than 80% with CTA or carotid duplex
Exclusion criteria
* Contraindication for carotid endarterectomy or stenting
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in RAVLT score | Six weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive tests of attention | Six weeks | Comparison in cognitive tests for attention between carotid endarterectomy and stenting |
| Cognitive tests for memory | Six weeks | Comparison in cognitive tests for memory between carotid endarterectomy and stenting |
| Cognitive tests for processing speed | Six weeks | Comparison in cognitive tests for processing speed between carotid endarterectomy and stenting |
| Cognitive tests of mood | Six weeks | Comparison in cognitive tests for mood between carotid endarterectomy and stenting |
| Tests of motor function | Six weeks | Comparison in cognitive tests for motor function between carotid endarterectomy and stenting |
| Cognitive tests for attention, memory, processing speed, mood, motor function, visual-spatial skills, executive functioning | Six weeks and six months | — |
| Cognitive tests of executive functioning | Six weeks | Comparison in cognitive tests for executive functioning between carotid endarterectomy and stenting |
| Cognitive tests of memory | Six weeks | Comparison in cognitive tests for memory between carotid endarterectomy and stenting |
| Cognitive tests of processing speed | Six months | Comparison in cognitive tests for processing speed between carotid endarterectomy and stenting |
| Difference in new ischemic infarcts in Diffusion - weighted MRI | Six weeks | Difference in new ischemic infarcts in Diffusion - weighted MRI |
| Cognitive tests of visual-spatial skills | Six weeks | Comparison in cognitive tests of visual-spatial skills between carotid endarterectomy and stenting |
Countries
United States
Outcome results
None listed