Laparoscopic Colonic Surgery
Conditions
Keywords
cytokine Transversus Abdominis Plane Block
Brief summary
The investigators designed a study to determine whether with combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokines in patients undergoing Laparoscopic Colonic Surgery.
Detailed description
The investigators designed a study to determine whether combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokine in patients undergoing Laparoscopic Colonic Surgery.
Interventions
DRUGtransversus abdominis plane block
transversus abdominis plane block with 20 mL saline
Sponsors
China Medical University, China
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* •Participants were deemed eligible if they were candidates for spinal anesthesia undergoing Laparoscopic Colonic Surgery
Exclusion criteria
* •Existing cognitive impairment as evidenced by Mini-Mental State Examination scores below 24 (of the 30 possible points) * A history of neurological and psychiatric diseases including stroke, and psychosis * Severe visual or hearing impairment * Unwillingness to comply with the protocol or procedures
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of cytokine level in plasma samples | just after anesthesia induction ; at the end of the surgery; 24h after surgery | The blood samples were collected before induction of anesthesia and at the end of surgery. |
Countries
China
Outcome results
None listed