Bronchoscopy Biopsy
Conditions
Brief summary
Bleeding during transbronchial ro endobronchial biopsy is rather a common complication. Mostly this is an insignificant bleeding, but in 3% of the biopsies there is a substantial amount of bleeding that requires a special treatment or follow up. The goal of this study is to examine whether submission of tranexamic acid during the biopsy could diminish the amount of bleeding.
Interventions
DRUGtranexamic acid
DRUGsaline
Sponsors
Liran Levy
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Patient that are candidates to endobronchial or transcronchial biopsy
Exclusion criteria
* S/P MI or CVA or PE or DVT . * S/P thrombophilia. * Patients under coagulation therpay * Chronic Renal Failure * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| amount of bleeding | participants will be followed for the duration of hospital stay, an expected average of one day | amount of bleedibg that will be calculated on the basis of the difference between the amount of saline that will be injected at the bronchoscopy and the blood and fluid that will be collected in the suction tank. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| amount of erythrocytes | participants will be followed for the duration of hospital stay, an expected average of one day | amount of erythrocytes by multiplying the Hematocrit and blood volume |
Countries
Israel
Contacts
Primary ContactLiran Levy, MD
Backup ContactLiran Levy, MD
Outcome results
None listed