Early Waning of Maternal Measles and Meningitis C Antibodies

Observation Study on Early Waning of Maternal Measles and Meningitis C Antibodies

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02219061

Acronym

EWMM

Enrollment

100

Registered

2014-08-18

Start date

2014-05-31

Completion date

2014-12-31

Last updated

2014-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Measles

Keywords

Measles, Meningitis C, waning, Geometric Mean Titer, China

Brief summary

Maternal antibodies (measles and meningitis C) may wane in the first six months after birth. * Geometric mean titers(GMTs) of measles and meningitis C. * Follow-up on 0 month, 3rd month,5th month and 7th month after birth.

Detailed description

Measles and meningitis C are hot topics in China in recent years. Although China had set the goal of measles elimination, many measles cases were found to be those aged \< 8 months and meningitis C is becoming public health issue since meningitis group A has been controlled at a very low level and little is known on C group. So the investigators designed the observation study on the two antibodies. Maternal antibodies are supposed to wane after birth. Serums of the placenta(0 month), children of 3 months, 5 months and 7 months old will be collected and the geometric mean titers (GMTs) of measles and meningitis C will be confirmed by using the ELISA test.

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 7 Months

Healthy volunteers

Yes

Inclusion criteria

* Healthy infants.

Exclusion criteria

* Infants with poor score.

Design outcomes

Primary

Measure	Time frame
Geometric Mean Titer	Up to six months

Countries

China

Contacts

Primary ContactChuanxi Fu, PhD

fuchuanxi@gmail.com+86 20 36055887

Outcome results